Publications

Effects of inhibition of Janus kinase signalling during controlled mechanical ventilation on the rate of skeletal muscle protein synthesis William J. Evans, Mahalakshmi Shankaran, Lars Larsson, Nicola Cacciani, Yvette Hedström, James L. Kirkland, Tamar Tchkonia, Hussein Mohammed, Tyler Field, Marc K. Hellerstein – 10/03/2025

Myosin Post-translational Modifications Associated with Critical Illness Myopathy. Fernando Ribeiro, Bruno Di Geronimo, Nicola Cacciani, Anna Widgren, Yvette Hedström, Anselmo S. Moriscot, Peter M. Kasson, Shina C. L. Kamerlin, Jonas Bergquist, Lars Larsson – 1/25/2025

Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: Mechanisms at the cellular and molecular levels.  Larsson, Li, Edström, Eriksson, Zackrisson, Argentini, Schiaffino – 1/28/2000

Sarcopenia: Aging-related Loss Of Muscle Mass And Function, American Physiological Society. Larsson, Degens, Li, Salviati, Lee, Thompson, Kirkland, and Sandri – 11/14/2018

Neurogenic vs. Myogenic Origin of Acquired Muscle Paralysis in Intensive Care Unit (ICU) Patients: Evaluation of Different Diagnostic Methods, “diagnostics” published by MDPI. Marrero, Stålberg, Cooray, Kalamgi, Hedström, Bellander, Nennesmo, and Larsson – 11/18/2020

Chaperone co-inducer BGP-15 mitigates early contractile dysfunction of the soleus muscle in a rat ICU model, National Center for Biotechnology Information Cacciani, Salah, Li, Akkad, Backeus, Hedstrom, Jena, Begquist, and Larsson – 12/18/2019

Mechanical Signaling in the Pathophysiology of Critical Illness Myopathy, Frontiers in Physiology Kalamgi and Larsson – 2/04/2016

Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms, Journal of Physiology (2011) Ochala, Gustafson, Llano Diez, Renaud, Li, Aare, Qaisar, Banduseela, HedstrÖm, Tang, Dworkin, Ford, Nair, Perera, Gautel, and Larsson – 2011

Time course analysis of mechanical ventilation-induced diaphragm contractile muscle dysfunction in the rat, Journal of Physiology (2014) Corpeno, Dworkin, Cacciani, Salah, Bergman, Ravara, Vitadello, Gorza, Gustafson, HedstrÖm, Petersson, Feng, Jin, Iwamoto, Yagi, Artemenko, Bergquist, and Larsson – 2014

Metabolomic Profiling of Respiratory Muscles and Lung in Response to Long-term Controlled Mechanical Ventilation, Frontiers in Cell and Developmental Biology Wen, Zhang, and Larsson – 3/22/2022

Critical Illness Myopathy: Diagnostic Approach and Resulting Therapeutic Implications – PMC (nih.gov) Rodriguez, Larsson, and Z’Graggen – 3/28/2022

The role of zinc and matrix metalloproteinases in myofibrillar protein degradation in critical illness myopathy, Free Radical Biology and Medicine Ribeiro, Zhang, Wen, Cacciani, HedstrÖm, Xia, Schulz, Larsson – 6/27/2024

The Sick And The Weak: Neuropathies/Myopathies In The Critically Ill, American Physiological Society O. Friedrich, M. B. Reid, G. Van den Berghe, I. Vanhorebeek, G. Hermans, M. M. Rich, and L. Larsson – 7/1/2015

A prospective clinical study on the mechanisms underlying critical illness myopathy—A time-course approach, Journal of Cachexia, Sarcopenia and Muscle (2022) Cacciani, Skärlén, Wen, Zhang, Addinsall, Llano-Diez, Li, Gransberg, Hedström, Bellander, Nelson, Bergquist, and Larsson – 9/12/2022